University of Pittsburgh

Charles A. Scanga, PhD

Research Associate Professor





	
	


			

		Dr. Scanga	
		

		

	
Contact

    		

		scangaca@pitt.edu	
		

		
			

		412-624-4385	
		

		
	
	
			

		Fax: 
		412-648-3394	
		

	    

    
    
   
    
   
    
    		

		
9014 Biomedical Science Tower 3
3501 Fifth Avenue
	
		

	    
    
   
   
   
   
   
   
    
    
	
	
	
			

		Pittsburgh, PA 15261-1308	
		

		
		
	



	
Education
	
	

	
PhD in Molecular Virology and Microbiology, University of Pittsburgh, School of Medicine
        

              
   
  
 
 


  
 
 
 
 
 
 
 
         
        
        
        
        
        
        
        
        
 
 
   
   
















        









	
Research Lab Affiliation
	
	

	Flynn Lab	
	













	
Publications
	
	

	
Scanga, C. A; and Flynn, J. L. (2010) Mycobacterial infections and the inflammatory seesaw. Cell Host Microbe. 7: 177-179. |  View Abstract
Sun, R; Skeiky, Y. A; Izzo, A; Dheenadhayalan, V; Imam, Z; Penn, E; Stagliano, K; Haddock, S; Mueller, S; Fulkerson, J; Scanga, C; Grover, A; Derrick, S. C; Morris, S; Hone, D. M; Horwitz, M. A; Kaufmann, S. H; and Sadoff, J. C. (2009) Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis. Vaccine. 27: 4412-4423. |  View Abstract
Magalhaes, I; Sizemore, D. R; Ahmed, R. K; Mueller, S; Wehlin, L; Scanga, C; Weichold, F; Schirru, G; Pau, M. G; Goudsmit, J; Kuhlmann-Berenzon, S; Spangberg, M; Andersson, J; Gaines, H; Thorstensson, R; Skeiky, Y. A; Sadoff, J; and Maeurer, M. (2008) rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector. PLoS One. 3: e3790.  |  View Abstract
Lee, K. S; Scanga, C. A; Bachelder, E. M; Chen, Q; and Snapper, C. M. (2007) TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae. Cell Immunol. 245: 103-110. |  View Abstract
Scanga, C. A; Bafica, A; and Sher, A. (2007) Viral gene expression in HIV transgenic mice is activated by Mycobacterium tuberculosis and suppressed after antimycobacterial chemotherapy. J Infect Dis. 195: 246-254.  |  View Abstract
Bafica, A; Scanga, C. A; Feng, C. G; Leifer, C; Cheever, A; and Sher, A. (2005) TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J Exp Med. 202: 1715-1724. |  View Abstract
Bafica, A; Scanga, C. A; Serhan, C; Machado, F; White, S; Sher, A; and Aliberti, J. (2005) Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. J Clin Invest. 115: 1601-1606. |  View Abstract