University of Pittsburgh

Berthony Deslouches, MD, PhD

Research Assistant Professor





	
	


			

		Dr. Deslouches	
		

		

	
Contact

    		

		tdesl19@pitt.edu	
		

		
			

		412-648-8874	
		

		
	
	
			

		Fax: 
		412-624-4440	
		

	    

    
    
   
    
   
    
    		

		
9026 Biomedical Science Tower 3
3501 Fifth Avenue
	
		

	    
    
   
   
   
   
   
   
    
    
	
	
	
			

		Pittsburgh, PA 15261	
		

		
		
	



	
Education
	
	

	
MD, PhD, Univeristy of Pittsburgh, 2008
MA in Biochemistry, City College of the City University of New York, 1995
BS in Anthropology and Biochemistry, City College of the City University of New York, 1993
        

              
   
  
 
 	
Research Summary
	
	

	
Our research focuses on the development of engineered antimicrobial peptides (eCAPs) for applications to hard-to-treat bacterial infections, particularly infections caused by multidrug-resistant pathogens.
	
	




  
 
 
 
 
 
 
 
         
        
        
        
        
        
        
        
        
 
 
   
   
















        


















	
Why I Chose Pitt
	
	

	
I graduated from University of Pittsburgh School of Medicine. I know this is a great institution!
	
	




	
Publications
	
	

	
Neal, M. D; Deslouches, B; and Ogilvie, J. (2009) The use of pre-operative imaging and intraoperative parathyroid hormone level to guide surgical management of tertiary hyperparathyroidism from X-linked hypophosphatemic rickets: a case report. Cases J. 2: 7572. |  View Abstract
Deslouches, B; Gonzalez, I. A; DeAlmeida, D; Islam, K; Steele, C; Montelaro, R. C; and Mietzner, T. A. (2007) De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia. J Antimicrob Chemother. 60: 669-672. |  View Abstract
Phadke, S. M; Deslouches, B; Hileman, S. E; Montelaro, R. C; Wiesenfeld, H. C; and Mietzner, T. A. (2005) Antimicrobial peptides in mucosal secretions: the importance of local secretions in mitigating infection. J Nutr. 135: 1289-1293. |  View Abstract
Deslouches, B; Phadke, S. M; Lazarevic, V; Cascio, M; Islam, K; Montelaro, R. C; and Mietzner, T. A. (2005) De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity. Antimicrob Agents Chemother. 49: 316-322. |  View Abstract
Deslouches, B; Islam, K; Craigo, J. K; Paranjape, S. M; Montelaro, R. C; and Mietzner, T. A. (2005) Activity of the de novo engineered antimicrobial peptide WLBU2 against Pseudomonas aeruginosa in human serum and whole blood: implications for systemic applications. Antimicrob Agents Chemother. 49: 3208-3216. |  View Abstract
Phadke, S. M; Islam, K; Deslouches, B; Kapoor, S. A; Beer Stolz, D; Watkins, S. C; Montelaro, R. C; Pilewski, J. M; and Mietzner, T. A. (2003) Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model. Peptides. 24: 1099-1107. |  View Abstract
Li, J; Deslouches, B; Cosloy, S. D; and Russell, C. S. (2003) A heme-deficient strain of Escherichia coli has a three-base pair deletion in a "hotspot" in hemA. Biochim Biophys Acta. 1626: 102-105. |  View Abstract